By car:

from North:
Autostrada del Sole A1 Highway towards Firenze-Roma, exit at Valdichiana, continue towards Perugia Terni E45 exiting at Todi – San Damiano
Autostrada del Sole A1 Highway, exit at Orvieto, continue towards Todi (on state road SS448)
Autostrada Adriatica A14 Highway, exit at Cesena, continue towards Perugia-Terni (E45), exit at Todi – San Damiano
Autostrada Adriatica A14 Highway, exit at Fano continuing on the Flaminia towards Gubbio – Todi.
from South:
Autostrada del Sole A1 Highway, towards Roma – Firenze, exit at Orte continue towards Terni- Perugia (E45), exit at Todi – San Damiano
Autostrada Adriatica A14 Highway exit at Pescara, continue towards L’Aquila (A25 highway) then to Rieti – Terni (on the E80), then towards Perugia on the E45, exit at Todi – San Damiano.

By train
National routes Ferrovie dello Stato: final destination P. San Giovanni Station, departing from Firenze-Terontola-Perugia National routes Ferrovie dello Stato: final destination P. San Giovanni Station, departing from Ancona – Falconara – Foligno – Perugia Regional routes Ferrovia Centrale Umbra final destination Todi, from P. San Giovanni Station from South: Roma – Orte – Terni (Ferrovie dello Stato) L’Aquila – rieti – Terni (Ferrovie dello Stato) Terni – Todi (Ferrovie Centrale Umbra)